Association of increased cortical thickness and cognitive impairment in patients with Kallmann syndrome
This study identified cortical thickening involved in fronto-limbic and default mode network as key neuroanatomical signatures of the patients with KS, which was associated with cognitive impairment. Specific genetic variants may further modulate the structural alterations and cognitive functioning in patients with KS.
Authors
- X.Y. Wang (ORCID: https://orcid.org/0000-0002-0075-2478)
- Haimiao Huang
- Yafang He
- Hailong Wu (ORCID: https://orcid.org/0009-0006-0997-4567)
- Yan Fu (ORCID: https://orcid.org/0000-0001-8300-4573)
- F. Wu
- Xiaoping Yi
- Meichao Men
- Alessandro Grecucci
- Jinfan Zhang
- Bihong T Chen
- Wenzhen Zhu
Institutions
- City Of Hope National Medical Center (US)
- Central South University (CN)
- University of Electronic Science and Technology of China (CN)
- Chongqing University (CN)
- Tokyo Medical University (JP)
- Hunan University (CN)
- University of Trento (IT)
- National Clinical Research (US)
- Chongqing Three Gorges Central Hospital (CN)
- Center for Neuroscience and Cognitive Systems (IT)
- Hainan General Hospital (CN)
- Chongqing Emergency Medical Center (CN)
- Department of Health (IE)
- Hainan Provincial Hospital of Traditional Chinese Medicine (CN)
- Xiangya Hospital Central South University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Chongqing Three Gorges University (CN)
- Arizona State University (US)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1093/ejendo/lvag019
- Primary Topic
- Hypothalamic control of reproductive hormones
- Type
- article
- Field-Weighted Citation Impact
- 0.00