Machine learning-based risk factors for acute-on-chronic liver failure in alcohol-associated liver disease

We developed a robust clinical prediction model combining LR and machine learning approaches. TBIL, folate, VitB12 and ΔPT are key prognostic markers that may enable early risk stratification and timely intervention, potentially reducing ACLF incidence in ALD patients.

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Publication Details

Journal
Annals of Medicine
Published
2026-01-30
DOI
https://doi.org/10.1080/07853890.2026.2621522
Primary Topic
Alcohol Consumption and Health Effects
Type
article
Field-Weighted Citation Impact
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article

Machine learning-based risk factors for acute-on-chronic liver failure in alcohol-associated liver disease

Jing Pan, Yan Wang, Linhui Hu, Suthat Liangpunsakul et al.
Annals of Medicine
Alcohol Consumption and Health Effects
article

Machine learning-based risk factors for acute-on-chronic liver failure in alcohol-associated liver disease

Jing Pan, Yan Wang, Linhui Hu, Suthat Liangpunsakul, Hao Cheng
article en

Abstract

We developed a robust clinical prediction model combining LR and machine learning approaches. TBIL, folate, VitB12 and ΔPT are key prognostic markers that may enable early risk stratification and timely intervention, potentially reducing ACLF incidence in ALD patients.

Annals of MedicineVol. 58(1)
Peking University (CN), Peking University First Hospital (CN), Indiana University – Purdue University Indianapolis (US)
Good health and well-being
Openalex Percentile: Top 73%
Alcohol Consumption and Health Effects
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