Seizure and quality-of-life outcomes following responsive neurostimulation treatment for drug-resistant epilepsy in children and young adults

The authors' cohort of young patients with severe drug-resistant epilepsy from a variety of etiologies experienced comparable improvements in seizure control at 12 months to that reported in adults at 9 years. Patients also reported improvements in quality of life. These robust outcomes may be due to empirical targeting of patient-specific seizure networks and rapid escalation of therapy to higher treatment parameters.

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Publication Details

Journal
Journal of Neurosurgery Pediatrics
Published
2026-01-30
DOI
https://doi.org/10.3171/2025.9.peds25200
Primary Topic
Neurological disorders and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Seizure and quality-of-life outcomes following responsive neurostimulation treatment for drug-resistant epilepsy in children and young adults

Ariana Philbin, Alexandra L. Geffrey, Nathan Sisterson, Hunki Kwon et al.
Journal of Neurosurgery Pediatrics
Neurological disorders and treatments
article

Seizure and quality-of-life outcomes following responsive neurostimulation treatment for drug-resistant epilepsy in children and young adults

Ariana Philbin, Alexandra L. Geffrey, Nathan Sisterson, Hunki Kwon, Nora Daly, Ziv M. Williams, Wen Shi, CJ Chu, R. Mark Richardson, Kristopher T. Kahle
article en

Abstract

The authors' cohort of young patients with severe drug-resistant epilepsy from a variety of etiologies experienced comparable improvements in seizure control at 12 months to that reported in adults at 9 years. Patients also reported improvements in quality of life. These robust outcomes may be due to empirical targeting of patient-specific seizure networks and rapid escalation of therapy to higher treatment parameters.

Journal of Neurosurgery Pediatrics
Kennedy Krieger Institute (US), Harvard University (US), Johns Hopkins University (US), Johns Hopkins Medicine (US), Massachusetts General Hospital (US)
Good health and well-being
Openalex Percentile: Top 73%
Neurological disorders and treatments
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