Small noncoding RNA TY2 enhances efferocytosis and improves outcomes in a mouse model of sepsis
TY2 is a drug based on a natural compound with potent anti-inflammatory effects. TY2 improved outcomes in mice with severe bacterial infection.
Authors
- Xaviar M Jones (ORCID: https://orcid.org/0000-0003-1815-4166)
- L. Li
- Hiroaki Komuro (ORCID: https://orcid.org/0000-0002-8249-6761)
- Eduardo Marbán
- Anh Nguyen
- Ahmed Gamal-Eldin Ibrahim
Publication Details
- Journal
- JCI Insight
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1172/jci.insight.196153
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cedars-Sinai Medical Center
- National Institutes of Health
- National Heart, Lung, and Blood Institute