Immunohistological Evaluation of Peri‐Implant Soft Tissue Grafting Using a Porcine Dermal Matrix—A Human Histological Study
The PDM used in this study exhibited no significant differences regarding epithelial changes, vascularization, tissue morphology, and collagen differentiation compared to a healthy control sample 3 months after grafting. The PDM group demonstrated a significantly higher frequency of CD68<sup>+</sup> and CD20<sup>+</sup> cells. The noticeable interindividual variation in immunoprofiles and clinical relevance of these findings should be investigated in future research.
Authors
- Tobias Fretwurst (ORCID: https://orcid.org/0000-0003-4769-7610)
- Susanne Nahles (ORCID: https://orcid.org/0000-0001-8522-0763)
- Florian Kernen (ORCID: https://orcid.org/0000-0002-3067-0756)
- Kajta Nelson
- Kirstin Vach (ORCID: https://orcid.org/0000-0001-9278-2203)
- L. Larsson
- V. C. Landwehr
- G. Iglhaut
- F. R. S. Michallek
- M. Sluka
Institutions
- Harvard University (US)
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
- Humboldt-Universität zu Berlin (DE)
- University of Gothenburg (SE)
Publication Details
- Journal
- Clinical Oral Implants Research
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1111/clr.70088
- Primary Topic
- Dental Implant Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bundesministerium für Bildung und Forschung
- Hanns-Seidel-Stiftung
- Oral Reconstruction Foundation