mTOR Modulation Affects Galectin-1 Expression in <i>KMT2A</i> -rearranged Acute Lymphoblastic Leukemia Cells
Targeting mTOR signaling contributes to the regulation of Galectin-1 immune checkpoint activity in <i>KMT2A</i>r-ALL. Inhibition of mTOR may represent a potential therapeutic strategy to overcome immune evasion in this leukemia subtype.
Authors
- Dawid P. Grzela (ORCID: https://orcid.org/0000-0002-0667-6488)
- Bartłomiej Pawlik (ORCID: https://orcid.org/0000-0002-8803-1033)
- Zuzanna Rydzyńska (ORCID: https://orcid.org/0000-0002-4419-1641)
- Justyna Walenciak (ORCID: https://orcid.org/0000-0001-6107-5936)
- Maciej Mazurek (ORCID: https://orcid.org/0000-0003-4317-8493)
- Joanna Madzio
Institutions
- Medical University of Warsaw (PL)
- Medical University of Lodz (PL)
- Institute for Medical Biology (PL)
- Postgraduate School of Molecular Medicine (PL)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Anticancer Research
- Published
- 2026-01-30
- DOI
- https://doi.org/10.21873/anticanres.17976
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00