Anti-CD320 Autoantibodies and Central Nervous System Vitamin B12 Deficiency in Idiopathic Myelopathy
ABCD is associated with a substantial proportion of IM. Screening for anti-CD320 followed by metabolic confirmation of a CNS-restricted B12 deficiency may be considered in the diagnostic evaluation of myelopathy.
Authors
- Samuel J. Pleasure (ORCID: https://orcid.org/0000-0001-8599-1613)
- Kelsey C. Zorn (ORCID: https://orcid.org/0000-0003-1227-2137)
- Matteo Gastaldi (ORCID: https://orcid.org/0000-0003-2288-2000)
- Corey N. Miller
- Felicia Chow
- John V. Pluvinage (ORCID: https://orcid.org/0000-0002-9607-2783)
- Sravani Kondapavulur (ORCID: https://orcid.org/0000-0002-4412-5978)
- Camilo Toro (ORCID: https://orcid.org/0000-0002-3917-9031)
- Vanja C. Douglas (ORCID: https://orcid.org/0000-0001-6955-8297)
- Elan L. Guterman (ORCID: https://orcid.org/0000-0003-0817-3144)
- Asritha Tubati (ORCID: https://orcid.org/0009-0003-5303-1214)
- Alyssa N. Nylander (ORCID: https://orcid.org/0000-0002-1976-3847)
- Leah Zuroff
- Ahmed Abdelhak (ORCID: https://orcid.org/0000-0001-9731-4169)
- Jeffrey Marc Gelfand (ORCID: https://orcid.org/0000-0002-5121-3319)
- Alexandra Galati
- Sydney Lee
- Yair Mina (ORCID: https://orcid.org/0000-0003-2311-6623)
- Chu-Yueh Guo
- Carson E. Moseley (ORCID: https://orcid.org/0000-0001-8859-3792)
- Megan Richie (ORCID: https://orcid.org/0000-0002-8802-7077)
- Max Liu (ORCID: https://orcid.org/0000-0001-6463-5046)
- Andrew McCaddon (ORCID: https://orcid.org/0000-0001-8588-9061)
- Andoni I. Asencor
- Madina Tugizova
- Jenny Linnoila
- Todd Nguyen
- Kathryn A. Kvam
- Neel S. Singhal
- Karen P. Ibarra
- Iyas Daghlas (ORCID: https://orcid.org/0000-0001-6924-0641)
- Mary Karalius
- Josiah Gerdts
- Sarah F. Wesley
- Colette M. Caspar (ORCID: https://orcid.org/0009-0008-6803-1600)
- Sarah B Berman
- Sonam Mohan
- Pietro Businaro
- Min Kang
- Ari J. Green
- Leena Suleiman
- Martineau Louine
- Benjamin Meyer
- Gary Alvarez Bravo
- Giacomo Greco
- Maulik Shah
- Yun-Han Huang
- Sukhman Sidhu
- Ariadna Gifreu
- Bruce Cree
- Colin Zamecnik
- Carlos A. Pardo
- Carolyn Bevan
- Thomas Martin
- David Acero-Garces
- John Engstrom
- Alexis Garcia Sarreon
- Krista McCutcheon
- Stefano Masciocchi
- John Neely
- Catherine G. Suen
- Ralph Green
- Stephen Hauser
Institutions
- San Francisco VA Medical Center (US)
- Johns Hopkins University (US)
- University of Pittsburgh (US)
- University of California, San Francisco (US)
- Neurosciences Institute (US)
- University of Utah (US)
- Universitat de Girona (ES)
- University of Pavia (IT)
- Johns Hopkins Medicine (US)
- National Human Genome Research Institute (US)
- Fondazione Istituto Neurologico Nazionale Casimiro Mondino (IT)
- Queen's Medical Center (US)
- University of California San Francisco Medical Center (US)
- National Institute of Neurological Disorders and Stroke (US)
- Institut d'Investigació Biomèdica de Girona (ES)
- Hospital Santa Caterina (ES)
- Palo Alto Institute (US)
- Kaiser Permanente San Jose Medical Center (US)
- Milford Hospital (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- Arc Research Institute
- Columbia University (US)
- University of California, Davis (US)
- Stanford University (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-01-30
- DOI
- https://doi.org/10.64898/2026.01.29.26345179
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00