A pathologically diagnosed multinodular and vacuolating neuronal tumor without typical multiple nodules: a case report
Multinodular and vacuolating neuronal tumors (MVNT) are glioneuronal and neuronal tumors classified as grade 1 in the 2021 World Health Organization classification of central nervous system tumors. These tumors are characterized by multiple nodules located between the deep cortex and subcortical white matter. Typically, patients are diagnosed radiologically and do not require treatment. This report describes a rare case of pathologically confirmed MVNT with radiological findings similar to those of low-grade glioma. Moreover, we highlight radiological features useful for differentiating MVNT from low-grade glioma.
Authors
- Takashi Sasayama (ORCID: https://orcid.org/0000-0002-5593-9045)
- Keiichiro Uehara (ORCID: https://orcid.org/0000-0002-6307-1186)
- Masamitsu Nishihara (ORCID: https://orcid.org/0000-0003-2926-5830)
- Tomoaki Harada (ORCID: https://orcid.org/0000-0001-5008-9910)
- Hiroaki Nagashima
- Ryota Kitano
- Kazuhiro Tanaka
Institutions
- Kobe City Nishi-Kobe Medical Center (JP)
- Kobe University (JP)
Publication Details
- Journal
- Frontiers in Radiology
- Published
- 2026-01-30
- DOI
- https://doi.org/10.3389/fradi.2026.1718759
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00