Sodium-glucose cotransporter-specific substrate αMG stimulates endogenous glucagon secretion and ameliorates obesity-associated metabolic disorders in mice
These results in this study suggest that αMG stimulates endogenous glucagon secretion and may lead to a therapeutic strategy for obesity-associated metabolic diseases.
Authors
- Yuichi Yamazaki (ORCID: https://orcid.org/0000-0002-8633-2983)
- Hiroki Tojima (ORCID: https://orcid.org/0000-0002-1646-2344)
- Yoshio Fujitani (ORCID: https://orcid.org/0000-0003-0196-4736)
- Daisuke Kohno (ORCID: https://orcid.org/0009-0001-1073-2745)
- Yuichi Ikeuchi (ORCID: https://orcid.org/0009-0004-3811-9469)
- Takumi Takizawa (ORCID: https://orcid.org/0000-0003-2169-0787)
- Takayoshi Suga (ORCID: https://orcid.org/0000-0001-8417-1461)
- Yoko Tabei
- Satoru Kakizaki (ORCID: https://orcid.org/0000-0002-1508-584X)
- Tadahiro Kitamura (ORCID: https://orcid.org/0000-0001-8809-8740)
- Ken Sato (ORCID: https://orcid.org/0000-0002-1858-6236)
- Osamu Kikuchi
- Yuko Nakagawa
- Masaki Kobayashi
- Toshio Uraoka
- Takashi Nishimura
Institutions
- Gunma University (JP)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1016/j.molmet.2026.102324
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00