Optic nerve imaging with OCT predicts disease progression and monitors brain and spinal atrophy in primary progressive multiple sclerosis
In PPMS, pRNFL predicts disability progression and greater retinal, brain, and SCA, supporting its role as a surrogate marker of neurodegeneration in clinical trials.
Authors
- Mar Tintoré
- Paula Tagliani (ORCID: https://orcid.org/0000-0002-4048-7314)
- Carmen Triadó Tur
- Pere Carbonell
- Manel Alberich
- Àlex Rovira (ORCID: https://orcid.org/0000-0002-2132-6750)
- Georgina Arrambide (ORCID: https://orcid.org/0000-0002-2657-5510)
- Agustín Pappolla (ORCID: https://orcid.org/0000-0001-6364-9497)
- Sergio Cabello
- Luciana Soledad Midaglia
- Sofía Sceppacuercia
- Ingrid Hernández Galán
- Xavier Montalban
- Andreu Vilaseca
- Joaquín Castilló
- René Carvajal
- Ana Zabalza
- Luca Bollo
- Jordi Rio
- Neus Mongay-Ochoa
- Deborah Pareto
- Manuel Comabella
- Breogan Rodriguez-Acevedo
- Àlvaro Cobo-Calvo
- Jaume Sastre-Garriga
Institutions
- Universitat de Vic - Universitat Central de Catalunya (ES)
- Universitat Autònoma de Barcelona (ES)
- Hospital de Sant Pau (ES)
- Vall d'Hebron Hospital Universitari (ES)
Publication Details
- Journal
- Multiple Sclerosis Journal
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1177/13524585251407976
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00