Double Jeopardy at the Neuromuscular Junction: Guillain–Barré Syndrome Overlapping with Myasthenia Gravis Challenges in Rehabilitation and Recovery

Abstract Guillain–Barré syndrome (GBS) and myasthenia gravis (MG) are distinct autoimmune neuromuscular disorders, but rare overlap can occur. Such coexistence complicates diagnosis, prolongs intensive care stay and challenges rehabilitation due to dual respiratory, bulbar and motor involvement. We report a patient initially diagnosed with GBS, later found to have overlapping MG, who underwent structured multidisciplinary rehabilitation. The case highlights the importance of individualised rehabilitation planning, vigilant respiratory management and structured follow-up in improving the outcomes.

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Publication Details

Journal
Indian Journal of Physical Medicine and Rehabilitation
Published
2026-01-30
DOI
https://doi.org/10.4103/ijpmr.ijpmr_61_25
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00
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article

Double Jeopardy at the Neuromuscular Junction: Guillain–Barré Syndrome Overlapping with Myasthenia Gravis Challenges in Rehabilitation and Recovery

Ravi Gaur, Megha Sunil, Veluguleti Ujwal, Nagma Sheenam et al.
Indian Journal of Physical Medicine and Rehabilitation
Myasthenia Gravis and Thymoma
article

Double Jeopardy at the Neuromuscular Junction: Guillain–Barré Syndrome Overlapping with Myasthenia Gravis Challenges in Rehabilitation and Recovery

Ravi Gaur, Megha Sunil, Veluguleti Ujwal, Nagma Sheenam, Nitesh Manohar Gonnade, T. K. Abins
article en

Abstract

Abstract Guillain–Barré syndrome (GBS) and myasthenia gravis (MG) are distinct autoimmune neuromuscular disorders, but rare overlap can occur. Such coexistence complicates diagnosis, prolongs intensive care stay and challenges rehabilitation due to dual respiratory, bulbar and motor involvement. We report a patient initially diagnosed with GBS, later found to have overlapping MG, who underwent structured multidisciplinary rehabilitation. The case highlights the importance of individualised rehabilitation planning, vigilant respiratory management and structured follow-up in improving the outcomes.

Indian Journal of Physical Medicine and Rehabilitation
All India Institute of Medical Sciences Jodhpur (IN)
Openalex Percentile: Top 73%
Myasthenia Gravis and Thymoma
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