Discontinuation of Renin–Angiotensin System Inhibitors and Risk of End‐Stage Renal Disease and Cardiovascular Outcomes Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Taiwanese Cohort Study

Our results support continuing RASi treatment even when the eGFR declines to below 45 mL/min/1.73 m<sup>2</sup> based on potential renal, cardiovascular, and survival benefits.

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Publication Details

Journal
Pharmacoepidemiology and Drug Safety
Published
2026-01-30
DOI
https://doi.org/10.1002/pds.70323
Primary Topic
Chronic Kidney Disease and Diabetes
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article
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article

Discontinuation of Renin–Angiotensin System Inhibitors and Risk of End‐Stage Renal Disease and Cardiovascular Outcomes Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Taiwanese Cohort Study

Yaa‐Hui Dong, Li‐Chiu Wu, Sengwee Toh, Chia‐Hsuin Chang
Pharmacoepidemiology and Drug Safety
Chronic Kidney Disease and Diabetes
article

Discontinuation of Renin–Angiotensin System Inhibitors and Risk of End‐Stage Renal Disease and Cardiovascular Outcomes Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Taiwanese Cohort Study

Yaa‐Hui Dong, Li‐Chiu Wu, Sengwee Toh, Chia‐Hsuin Chang
article en

Abstract

Our results support continuing RASi treatment even when the eGFR declines to below 45 mL/min/1.73 m<sup>2</sup> based on potential renal, cardiovascular, and survival benefits.

Pharmacoepidemiology and Drug SafetyVol. 35(2)
Harvard University (US), National Yang Ming Chiao Tung University (TW), National Taiwan University (TW), Harvard Pilgrim Health Care (US), National Taiwan University Hospital (TW)
Good health and well-being
Openalex Percentile: Top 76%
Chronic Kidney Disease and Diabetes
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