Quercetin regulates autophagy and attenuates airway inflammation in a murine model of asthma: association with PI3K/Akt/mTOR signaling pathway modulation
Quercetin attenuates airway inflammation and lung damage in asthmatic mice. Its therapeutic effect is associated with the modulation of PI3K/Akt/mTOR signaling pathway activity and the regulation of excessive autophagy, which provides new potential approaches and mechanistic insights for asthma treatment.
Authors
- H. LIU
- Jialin Zhang (ORCID: https://orcid.org/0000-0003-2617-2735)
- Wen Zhang (ORCID: https://orcid.org/0000-0001-5166-0736)
- Liye Lang
- Sheng Liu
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-30
- DOI
- https://doi.org/10.3389/fphar.2026.1755094
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wu Jieping Medical Foundation