Modulation of Renal FOXO3 Gene Expression by Urolithin A in a Rat Model of Renal Ischemia-Reperfusion Injury

Conclusions: These findings suggest that Urolithin A produces nephroprotective effects against IRI via modulating oxidative stress, inflammation, and apoptosis, particularly through the control of FOXO3. This study suggests that Urolithin A is a good treatment candidate for renal IRI control.

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Journal
Wiadomości Lekarskie
Published
2025-12-30
DOI
https://doi.org/10.36740/wlek/214626
Primary Topic
Pomegranate: compositions and health benefits
Type
article
Field-Weighted Citation Impact
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article

Modulation of Renal FOXO3 Gene Expression by Urolithin A in a Rat Model of Renal Ischemia-Reperfusion Injury

Munther Abosaooda, Qayssar Joudah Fadheel
Wiadomości Lekarskie
Pomegranate: compositions and health benefits
article

Modulation of Renal FOXO3 Gene Expression by Urolithin A in a Rat Model of Renal Ischemia-Reperfusion Injury

Munther Abosaooda, Qayssar Joudah Fadheel
article en

Abstract

Conclusions: These findings suggest that Urolithin A produces nephroprotective effects against IRI via modulating oxidative stress, inflammation, and apoptosis, particularly through the control of FOXO3. This study suggests that Urolithin A is a good treatment candidate for renal IRI control.

Wiadomości LekarskieVol. 78(12)
University of Babylon (IQ), Iraqi University (IQ)
Good health and well-being
Openalex Percentile: Top 31%
Pomegranate: compositions and health benefits
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