Dermoscopy of Subungual Squamous Cell Carcinoma: A Systematic Review

Dermoscopy reliably identifies features, particularly hyperkeratosis, onycholysis, irregular margins and hemorrhagic spots, that are common in invasive subungual squamous cell carcinoma; in situ disease more commonly presents with pigmentary changes. Recognition of these signs should lower the threshold for biopsy of suspicious single-digit nail lesions and may facilitate earlier diagnosis and treatment.

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Publication Details

Journal
Cancers
Published
2026-01-30
DOI
https://doi.org/10.3390/cancers18030446
Primary Topic
Nail Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Dermoscopy of Subungual Squamous Cell Carcinoma: A Systematic Review

Dominika Kwiatkowska, Elizabeth Lazaridou, Styliani Siskou, Myrto Trakatelli et al.
Cancers
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Dermoscopy of Subungual Squamous Cell Carcinoma: A Systematic Review

Dominika Kwiatkowska, Elizabeth Lazaridou, Styliani Siskou, Myrto Trakatelli, Aikaterini Patsatsi, Anastasia Trigoni, Ewelina Mazur, Zoé Apalla, Adam Reich, Christina Kemanetzi
article en

Abstract

Dermoscopy reliably identifies features, particularly hyperkeratosis, onycholysis, irregular margins and hemorrhagic spots, that are common in invasive subungual squamous cell carcinoma; in situ disease more commonly presents with pigmentary changes. Recognition of these signs should lower the threshold for biopsy of suspicious single-digit nail lesions and may facilitate earlier diagnosis and treatment.

CancersVol. 18(3)
Papageorgiou General Hospital (GR), University of Rzeszów (PL)
Openalex Percentile: Top 72%
Nail Diseases and Treatments
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