A comparative evaluation of efficacy of lignocaine and dexmedetomidine to attenuate hemodynamic and airway responses to endotracheal extubation in elective coronary artery bypass graft surgery: a prospective randomized double-blind clinical study

A single dose of dexmedetomidine (0.5 µg/kg) given 5 min prior to extubation significantly reduced post-extubation HR and improved extubation quality compared with lignocaine (1.5 mg/kg) in patients undergoing on-pump CABG surgeries.

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Publication Details

Journal
Anesthesia and Pain Medicine
Published
2026-01-30
DOI
https://doi.org/10.17085/apm.25239
Primary Topic
Anesthesia and Sedative Agents
Type
article
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article

A comparative evaluation of efficacy of lignocaine and dexmedetomidine to attenuate hemodynamic and airway responses to endotracheal extubation in elective coronary artery bypass graft surgery: a prospective randomized double-blind clinical study

Alok Kumar Bharti, Abhinav Kumar, Mumtaz Hussain, Mithilesh Kumar et al.
Anesthesia and Pain Medicine
Anesthesia and Sedative Agents
article

A comparative evaluation of efficacy of lignocaine and dexmedetomidine to attenuate hemodynamic and airway responses to endotracheal extubation in elective coronary artery bypass graft surgery: a prospective randomized double-blind clinical study

Alok Kumar Bharti, Abhinav Kumar, Mumtaz Hussain, Mithilesh Kumar, Arvind Kumar
article en

Abstract

A single dose of dexmedetomidine (0.5 µg/kg) given 5 min prior to extubation significantly reduced post-extubation HR and improved extubation quality compared with lignocaine (1.5 mg/kg) in patients undergoing on-pump CABG surgeries.

Anesthesia and Pain MedicineVol. 21(1)
Indira Gandhi Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 71%
Anesthesia and Sedative Agents
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