Host restriction factor SAMHD1 does not restrict seasonal influenza virus replication in human epithelial or macrophage-like cells
Together, these studies indicate that neither endogenous nor DOX-inducible SAMHD1 restricts the growth of seasonal IAV in macrophage-like or epithelial cells.
Authors
- Yongyan Xia (ORCID: https://orcid.org/0000-0002-9209-3173)
- Sofía Soler (ORCID: https://orcid.org/0000-0003-2939-6267)
- Rayk Behrendt (ORCID: https://orcid.org/0000-0002-1091-2877)
- Andrëw G. Brööks (ORCID: https://orcid.org/0000-0002-4085-9683)
- Rubaiyea Farrukee (ORCID: https://orcid.org/0000-0001-9023-246X)
- Sarah L. Londrigan (ORCID: https://orcid.org/0000-0003-0989-4971)
- Eva Bartok (ORCID: https://orcid.org/0000-0003-0556-1950)
- Patrick C. Reading
Institutions
- University of Bonn (DE)
- University Hospital Bonn (DE)
- Victorian Infectious Diseases Reference Laboratory (AU)
- Peter Doherty Institute (AU)
Publication Details
- Journal
- Virology Journal
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1186/s12985-026-03065-w
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00