Data From a Tertiary Care Center Reveal the Prevalence of Hepatitis B Among the Visiting Population
ELISA and subsequent RT-PCR analysis confirmed 165 positive cases. The positivity rates among males and females were 62.19% and 37.80%, respectively, with the highest proportion of cases originating from Sonitpur district, Assam. The most affected age groups were 21-40 and 41-60 years. Positive likelihood ratio analysis (baseline 2000 IU/mL) showed that diarrhea, pain, and vomiting were strongly associated with higher viral loads. Conclusions: Data on HBV cases across different ethnic groups revealed seasonal spikes from mid-spring to summer, with male predominance in the 21-60 age range. Diarrhea, dysentery, and abdominal pain were common symptoms, affecting both tribal and non-tribal populations equally. Although most cases are serologically positive irrespective of viral load, studies tracking associated prevalent symptoms and likelihood ratios may help identify predictive therapeutic approaches to prevent HBV infection from becoming epidemic.
Authors
- Sonuwara Begum
- Kausik Das (ORCID: https://orcid.org/0000-0001-6602-5516)
- Syed Tanwir Alam
- Sanjay K Sarkar
- Samrat Biswas
- Mihirjyoti Pathak
Institutions
- Gauhati Medical College and Hospital (IN)
- Tezpur Medical College & Hospital (IN)
Publication Details
- Journal
- Cureus
- Published
- 2026-01-30
- DOI
- https://doi.org/10.7759/cureus.102675
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Indian Council of Medical Research