Data From a Tertiary Care Center Reveal the Prevalence of Hepatitis B Among the Visiting Population

ELISA and subsequent RT-PCR analysis confirmed 165 positive cases. The positivity rates among males and females were 62.19% and 37.80%, respectively, with the highest proportion of cases originating from Sonitpur district, Assam. The most affected age groups were 21-40 and 41-60 years. Positive likelihood ratio analysis (baseline 2000 IU/mL) showed that diarrhea, pain, and vomiting were strongly associated with higher viral loads. Conclusions: Data on HBV cases across different ethnic groups revealed seasonal spikes from mid-spring to summer, with male predominance in the 21-60 age range. Diarrhea, dysentery, and abdominal pain were common symptoms, affecting both tribal and non-tribal populations equally. Although most cases are serologically positive irrespective of viral load, studies tracking associated prevalent symptoms and likelihood ratios may help identify predictive therapeutic approaches to prevent HBV infection from becoming epidemic.

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Publication Details

Journal
Cureus
Published
2026-01-30
DOI
https://doi.org/10.7759/cureus.102675
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Data From a Tertiary Care Center Reveal the Prevalence of Hepatitis B Among the Visiting Population

Sonuwara Begum, Kausik Das, Syed Tanwir Alam, Sanjay K Sarkar et al.
Cureus
Hepatitis B Virus Studies
article

Data From a Tertiary Care Center Reveal the Prevalence of Hepatitis B Among the Visiting Population

Sonuwara Begum, Kausik Das, Syed Tanwir Alam, Sanjay K Sarkar, Samrat Biswas, Mihirjyoti Pathak
article en

Abstract

ELISA and subsequent RT-PCR analysis confirmed 165 positive cases. The positivity rates among males and females were 62.19% and 37.80%, respectively, with the highest proportion of cases originating from Sonitpur district, Assam. The most affected age groups were 21-40 and 41-60 years. Positive likelihood ratio analysis (baseline 2000 IU/mL) showed that diarrhea, pain, and vomiting were strongly associated with higher viral loads. Conclusions: Data on HBV cases across different ethnic groups revealed seasonal spikes from mid-spring to summer, with male predominance in the 21-60 age range. Diarrhea, dysentery, and abdominal pain were common symptoms, affecting both tribal and non-tribal populations equally. Although most cases are serologically positive irrespective of viral load, studies tracking associated prevalent symptoms and likelihood ratios may help identify predictive therapeutic approaches to prevent HBV infection from becoming epidemic.

CureusVol. 18(1)
Gauhati Medical College and Hospital (IN), Tezpur Medical College & Hospital (IN)
Indian Council of Medical Research
Good health and well-being
Openalex Percentile: Top 72%
Hepatitis B Virus Studies
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