Nanoluciferase-CD63 labeling reveals extracellular vesicle kinetics in a mouse intraductal model of ductal carcinoma in situ
These findings demonstrate systemic dissemination of tumor-derived sEVs during DCIS progression, suggesting roles in early microenvironmental conditioning and metastatic preconditioning prior to overt invasion.
Authors
- Alexander Filatenkov (ORCID: https://orcid.org/0000-0002-5165-4173)
- Elizabeth A. Wellberg (ORCID: https://orcid.org/0000-0001-7342-390X)
- Sugantha Priya Elayapillai (ORCID: https://orcid.org/0000-0001-5596-7663)
- Samrita Dogra (ORCID: https://orcid.org/0000-0003-0831-4525)
- Bethany N. Hannafon (ORCID: https://orcid.org/0000-0003-0596-9171)
- Matthew Bruns (ORCID: https://orcid.org/0000-0001-8372-1353)
- Cole Hladik
Institutions
- The University of Kansas Cancer Center (US)
- University of Oklahoma Health Sciences Center (US)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1186/s13058-026-02221-y
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00