Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics

SB may regulate TRP-induced bone metabolism abnormalities in LNCaP cells through the IL-17 signaling pathway as well as five DEPs: p-ERK2, RELA, HSP90B1, GNAI1and GNAI3.

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Publication Details

Journal
PLoS ONE
Published
2026-01-29
DOI
https://doi.org/10.1371/journal.pone.0341064
Primary Topic
Silymarin and Mushroom Poisoning
Type
article
Field-Weighted Citation Impact
0.00

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article

Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics

Ying Jiang, Jianhui Li, Xuejiao Lv
PLoS ONE
Silymarin and Mushroom Poisoning
article

Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics

Ying Jiang, Jianhui Li, Xuejiao Lv
article en

Abstract

SB may regulate TRP-induced bone metabolism abnormalities in LNCaP cells through the IL-17 signaling pathway as well as five DEPs: p-ERK2, RELA, HSP90B1, GNAI1and GNAI3.

PLoS ONEVol. 21(1)
Heilongjiang University of Chinese Medicine (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 74%
Silymarin and Mushroom Poisoning
DOIOpen Access PDFOpenAlex
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