Immunohistochemical Analysis of STAT3 and ITGB6 in Oral Squamous Cell Carcinoma: Prognostic Relevance for Lymph Node Metastasis and Overall Survival
On the basis of our findings, STAT3 and ITGB6 were statistically associated with lymph node metastasis. Thus, we hypothesised that their increased expression can lead to the migration of cancer cells, resulting in lymph node metastasis and affecting overall survival. Further understanding of the signalling pathways mediating STAT3 and ITGB6 may help identify valid therapeutic targets for OSCC patients.
Authors
- Priya Kumar (ORCID: https://orcid.org/0000-0001-6456-0224)
- Aadithya B. Urs (ORCID: https://orcid.org/0000-0002-1299-5805)
- Garima Rawat (ORCID: https://orcid.org/0000-0001-6554-0444)
- Shivangni Rajoria
- Hema Malini Aiyer (ORCID: https://orcid.org/0000-0002-3167-6500)
- Anshuman Kumar
Institutions
- Narayana Health (IN)
- Maulana Azad Institute of Dental Sciences (IN)
- Society of Surgical Oncology (US)
Publication Details
- Journal
- Applied immunohistochemistry & molecular morphology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1097/pai.0000000000001309
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00