Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

Our findings suggest that increasing dosages targeting WB tacrolimus concentrations may not be necessary during pregnancy based on plasma tacrolimus concentrations. However, larger studies are needed to confirm the findings.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2026-01-29
DOI
https://doi.org/10.1002/bcp.70454
Primary Topic
Pregnancy and Medication Impact
Type
article
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article

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

Jildau R. Meinderts, Jelmer R. Prins, Paola Mian, Daan Touw et al.
British Journal of Clinical Pharmacology
Pregnancy and Medication Impact
article

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

Jildau R. Meinderts, Jelmer R. Prins, Paola Mian, Daan Touw, Frederike G I Van Vilsteren, Margriet F. C. de Jong, Karien M. H. van de Wetering
article en

Abstract

Our findings suggest that increasing dosages targeting WB tacrolimus concentrations may not be necessary during pregnancy based on plasma tacrolimus concentrations. However, larger studies are needed to confirm the findings.

British Journal of Clinical Pharmacology
University Medical Center Groningen (NL), University of Groningen (NL)
Good health and well-being
Openalex Percentile: Top 75%
Pregnancy and Medication Impact
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