An Optimized Staining Method for Visualization of Thermally Denatured Dermal Collagen

The novel protocol enables direct, high-contrast, and reproducible visualization of thermally denatured collagen using standard equipment in a short time. It holds promise as a practical histological tool in EBD and burn research, where precise collagen damage visualization is essential.

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Publication Details

Journal
Lasers in Surgery and Medicine
Published
2026-01-28
DOI
https://doi.org/10.1002/lsm.70101
Primary Topic
Collagen: Extraction and Characterization
Type
article
Field-Weighted Citation Impact
0.00

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article

An Optimized Staining Method for Visualization of Thermally Denatured Dermal Collagen

Dieter Manstein, Ga Ram Ahn, John Warner‐Levy, Heather M. Downs et al.
Lasers in Surgery and Medicine
Collagen: Extraction and Characterization
article

An Optimized Staining Method for Visualization of Thermally Denatured Dermal Collagen

Dieter Manstein, Ga Ram Ahn, John Warner‐Levy, Heather M. Downs, Sarfaraz Ahmed Quadri, Parita T.Suwan, Michael Wang‐Evers
article en

Abstract

The novel protocol enables direct, high-contrast, and reproducible visualization of thermally denatured collagen using standard equipment in a short time. It holds promise as a practical histological tool in EBD and burn research, where precise collagen damage visualization is essential.

Lasers in Surgery and MedicineVol. 58(3)
Harvard University (US), Manchester Academic Health Science Centre (GB), University of Manchester (GB), Massachusetts General Hospital (US)
Massachusetts General Hospital
Affordable and clean energy
Openalex Percentile: Top 76%
Collagen: Extraction and Characterization
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