PFKFB3 exacerbates myocardial injury by accelerating CXCR4hi neutrophil mobilization after acute myocardial infarction
PFKFB3 exacerbates AMI-induced myocardial inflammatory injury by accelerating CXCR4hi neutrophil mobilization. The mechanism involves PFKFB3-mediated reprogramming of glycolytic metabolism.
Authors
- Zongying Yu
- Dadong Liu (ORCID: https://orcid.org/0000-0002-8610-7620)
- Wutao Wang
- Qin Zhu
- Yingjia Xu
- Danrui Wang
- Min Xiao
Institutions
- Shanghai Jiao Tong University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Jiading District Central Hospital (CN)
- Wujiang District People's Hospital (CN)
- The Fifth People’s Hospital of Suzhou (CN)
- Nanjing University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1371/journal.pone.0333657
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00