Causal Associations Between Gut Microbes and Heart Failure Across Multiple Etiologies: A Mendelian Randomization Study
Genetically predicted enrichment of <i>Peptostreptococcaceae</i> is causally associated with a lower risk of hypertensive heart disease. These MR findings warrant a mechanistic dissection of <i>Peptostreptococcaceae</i>-mediated pathways as a potential therapeutic lever for the prevention and treatment of hypertension-mediated HF.
Authors
- Safraz Anwar (ORCID: https://orcid.org/0009-0007-6080-8174)
- Yun-peng Shang
- Xiaogang Guo (ORCID: https://orcid.org/0000-0002-7231-8566)
- Xinming Xu
- Xiao Cui
Institutions
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Reviews in Cardiovascular Medicine
- Published
- 2026-01-22
- DOI
- https://doi.org/10.31083/rcm46534
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China