Abnormal Pro-inflammatory Immune Cell Responses Precede Clinical Onset of Hypertensive Disorders of Pregnancy
We identify a pro-inflammatory cellular immune signature in pregnant individuals destined to have HDP. Immune signatures may serve as a new biomarker to identify subsets of individuals at particular risk for HDP and point to new therapeutic targets to prevent HDP.
Authors
- Liqhwa Ncube
- Michal A. Elovitz (ORCID: https://orcid.org/0000-0001-7554-7180)
- Chelsea A. DeBolt (ORCID: https://orcid.org/0000-0002-9532-4109)
- Gautier Bréville (ORCID: https://orcid.org/0000-0003-0890-1981)
- Amit Bar‐Or (ORCID: https://orcid.org/0000-0001-7179-0335)
- Ayman Rezk (ORCID: https://orcid.org/0000-0001-8026-6308)
- R. C. Li
- Valerie A. Riis
- Fatoumata Barry
Institutions
- Associates in Women’s Health (US)
- University of Pennsylvania (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Hypertension
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25680
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00