Should Preoperative Biliary Decontamination Be Considered to Minimize Morbidity and Mortality Following Pancreatoduodenectomy?
Bacteriobilia contributes to postoperative complications and serves as a predictor of poorer survival after PD. Standard perioperative antibiotic prophylaxis in PD is insufficient. Based on our findings, perioperative antibiotic therapy with amoxicillin/clavulanic acid and gentamicin combination appears to provide superior coverage and may improve postoperative morbidity and overall survival following PD.
Authors
- Tomasz Guzel (ORCID: https://orcid.org/0000-0003-0911-7742)
- Natalia Olszewska (ORCID: https://orcid.org/0000-0001-5585-6082)
- Agnieszka Milner
- Edyta Podsiadły (ORCID: https://orcid.org/0000-0002-1897-6568)
- Piotr Paluszkiewicz (ORCID: https://orcid.org/0000-0002-7993-1654)
- Maciej Słodkowski (ORCID: https://orcid.org/0000-0002-3881-5753)
Institutions
- Medical University of Warsaw (PL)
Publication Details
- Journal
- Antibiotics
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3390/antibiotics15020134
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 24.20
Funders
- Warszawski Uniwersytet Medyczny
- Uniwersytet Warszawski