A Comparison of Ten Large Language Models and a Conventional Search Engine for Clinical Decision Support in Anesthesiology: Expert Agreement and Physician Perceptions

Although LLM-generated responses differed in quality, DeepSeek R1 and Claude-Sonnet 3.5 produced answers most consistent with expert clinical judgment. The poor performance of several models, coupled with clinician skepticism, underscores the need for further validation before integrating AI into routine anesthesiology decision support.

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Publication Details

Journal
Anesthesia & Analgesia
Published
2026-01-29
DOI
https://doi.org/10.1213/ane.0000000000007864
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

A Comparison of Ten Large Language Models and a Conventional Search Engine for Clinical Decision Support in Anesthesiology: Expert Agreement and Physician Perceptions

Thomas M. Hemmerling, Pascal Laferrière-Langlois, Sean Jeffries, Anil K. Sinha et al.
Anesthesia & Analgesia
Artificial Intelligence in Healthcare and Education
article

A Comparison of Ten Large Language Models and a Conventional Search Engine for Clinical Decision Support in Anesthesiology: Expert Agreement and Physician Perceptions

Thomas M. Hemmerling, Pascal Laferrière-Langlois, Sean Jeffries, Anil K. Sinha, Robert Harutyunyan, Oliver Cafferty, Eric D. Pelletier, Louis-Pierre Poulin
article en

Abstract

Although LLM-generated responses differed in quality, DeepSeek R1 and Claude-Sonnet 3.5 produced answers most consistent with expert clinical judgment. The poor performance of several models, coupled with clinician skepticism, underscores the need for further validation before integrating AI into routine anesthesiology decision support.

Anesthesia & Analgesia
McGill University (CA), Université de Montréal (CA)
Peace, Justice and strong institutions
Openalex Percentile: Top 75%
Artificial Intelligence in Healthcare and Education
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