Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia

The search for an ideal anesthetic has always been a major goal in anesthesiology. In recent years, the introduction of ciprofol has marked a major breakthrough in the pharmacological field, following the introduction of dexmedetomidine. Ciprofol has similar characteristics to propofol but with greater hemodynamic stability. Furthermore, it overcomes one of the most common discomforts associated with propofol: pain at the injection site. These characteristics make it a suitable hypnotic for pediatric use. Although studies on children are still limited, the literature on adults is now substantial and of high quality. The potential advantages of using ciprofol in pediatric anesthesia include pain-free induction, hemodynamic stability, less respiratory depression, and a lower incidence of emergence delirium.

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Journal
Children
Published
2026-01-29
DOI
https://doi.org/10.3390/children13020188
Primary Topic
Anesthesia and Sedative Agents
Type
article
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article

Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia

Giuliano Marchetti, Pasquale Buonanno, Cecilia Maria Pizzo, Giuseppe Servillo et al.
Children
Anesthesia and Sedative Agents
article

Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia

Giuliano Marchetti, Pasquale Buonanno, Cecilia Maria Pizzo, Giuseppe Servillo, Elisa Francia, Ilaria Mascilini, Cecilia Di Fabio, Valentina Di Conza, Teresa Grimaldi Capitello, Marco Cascella
article en

Abstract

The search for an ideal anesthetic has always been a major goal in anesthesiology. In recent years, the introduction of ciprofol has marked a major breakthrough in the pharmacological field, following the introduction of dexmedetomidine. Ciprofol has similar characteristics to propofol but with greater hemodynamic stability. Furthermore, it overcomes one of the most common discomforts associated with propofol: pain at the injection site. These characteristics make it a suitable hypnotic for pediatric use. Although studies on children are still limited, the literature on adults is now substantial and of high quality. The potential advantages of using ciprofol in pediatric anesthesia include pain-free induction, hemodynamic stability, less respiratory depression, and a lower incidence of emergence delirium.

ChildrenVol. 13(2)
University of Salerno (IT), Università Campus Bio-Medico (IT), University of L'Aquila (IT), San Salvatore Hospital (IT), Federico II University Hospital (IT), Bambino Gesù Children's Hospital (IT), University of Naples Federico II (IT)
Good health and well-being
Openalex Percentile: Top 72%
Anesthesia and Sedative Agents
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