Prognostic determinants of survival in early-stage endometrial cancer: A retrospective analysis

Histologic grade was the strongest independent prognostic factor for OS and DFS in early-stage EC, surpassing tumor stage, myometrial invasion, and LVSI. These findings highlight the importance of comprehensive surgical staging, especially when high-grade tumors are detected intraoperatively, to ensure accurate risk stratification and appropriate use of adjuvant therapies.

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Publication Details

Journal
Journal of Turkish Society of Obstetric and Gynecology
Published
2026-01-29
DOI
https://doi.org/10.4274/tjod.galenos.2026.23934
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic determinants of survival in early-stage endometrial cancer: A retrospective analysis

Şeyma Yaşar, Nesibe Zeyveli Çelik, Rauf Melekoğlu, Ercan Yılmaz
Journal of Turkish Society of Obstetric and Gynecology
Endometrial and Cervical Cancer Treatments
article

Prognostic determinants of survival in early-stage endometrial cancer: A retrospective analysis

Şeyma Yaşar, Nesibe Zeyveli Çelik, Rauf Melekoğlu, Ercan Yılmaz
article en

Abstract

Histologic grade was the strongest independent prognostic factor for OS and DFS in early-stage EC, surpassing tumor stage, myometrial invasion, and LVSI. These findings highlight the importance of comprehensive surgical staging, especially when high-grade tumors are detected intraoperatively, to ensure accurate risk stratification and appropriate use of adjuvant therapies.

Journal of Turkish Society of Obstetric and Gynecology
Inonu University (TR), Malatya Devlet Hastanesi (TR)
Good health and well-being
Openalex Percentile: Top 75%
Endometrial and Cervical Cancer Treatments
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