Exploring the relationship between metabolism and immune microenvironment in breast cancer bone metastasis based on metabolic pathways

This study reveals the prognostic metabolic pathways and important prognostic target genes in BCBM from the perspective of metabolism-immunity interaction. MRGs can well distinguish the prognosis of different patients, and metabolism-related risk modeling can be used as a good prognostic predictor, which provides valuable insights into the "metabolic-immune" perspective of treatment.

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Publication Details

Journal
PLoS ONE
Published
2026-01-29
DOI
https://doi.org/10.1371/journal.pone.0341270
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploring the relationship between metabolism and immune microenvironment in breast cancer bone metastasis based on metabolic pathways

Changyou Yang, Yi Qin, Zhaofeng Li, Guojian Li et al.
PLoS ONE
Cancer, Hypoxia, and Metabolism
article

Exploring the relationship between metabolism and immune microenvironment in breast cancer bone metastasis based on metabolic pathways

Changyou Yang, Yi Qin, Zhaofeng Li, Guojian Li, Houlin Mi
article en

Abstract

This study reveals the prognostic metabolic pathways and important prognostic target genes in BCBM from the perspective of metabolism-immunity interaction. MRGs can well distinguish the prognosis of different patients, and metabolism-related risk modeling can be used as a good prognostic predictor, which provides valuable insights into the "metabolic-immune" perspective of treatment.

PLoS ONEVol. 21(1)
Zhuhai People's Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 74%
Cancer, Hypoxia, and Metabolism
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