Multimodal Enhancement of Colonic Motility by Acupuncture at ST36 is Mediated by TRPV1+ Cutaneous Sensory Fibers

Through the use of spatiotemporally precise optogenetic control, our study revealed that TRPV1<sup>+</sup> sensory fibers at ST36 are the major convergent pathway for multimodal (electrical/mechanical/thermal/chemical) enhancement of colorectal motility by acupuncture.

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Publication Details

Journal
Frontiers in Bioscience-Landmark
Published
2026-01-21
DOI
https://doi.org/10.31083/fbl46975
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Multimodal Enhancement of Colonic Motility by Acupuncture at ST36 is Mediated by TRPV1+ Cutaneous Sensory Fibers

H. Chen, Xiaodong Li, Wang Li, Bing Zhu et al.
Frontiers in Bioscience-Landmark
Gastrointestinal motility and disorders
article

Multimodal Enhancement of Colonic Motility by Acupuncture at ST36 is Mediated by TRPV1+ Cutaneous Sensory Fibers

H. Chen, Xiaodong Li, Wang Li, Bing Zhu, Xinyan Gao, Sha Li, Nan Zhang, Kun Liu
article en

Abstract

Through the use of spatiotemporally precise optogenetic control, our study revealed that TRPV1<sup>+</sup> sensory fibers at ST36 are the major convergent pathway for multimodal (electrical/mechanical/thermal/chemical) enhancement of colorectal motility by acupuncture.

Frontiers in Bioscience-LandmarkVol. 31(1)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), China Academy of Chinese Medical Sciences (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 73%
Gastrointestinal motility and disorders
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