Longitudinal corneal thickness changes and their relation to ocular and systemic cardiovascular risk factors: Results from the Gutenberg Health Study

While observing a 5-year decline in CCT, peripheral corneal thickness remained relatively stable. We observed longitudinal associations between CCT changes and HbA1c, lipid profile, mean arterial pressure and smoking, suggesting that corneal thickness changes may be influenced by cardiovascular and metabolic health and thus may be taken into consideration in glaucoma risk stratification.

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Publication Details

Journal
Acta Ophthalmologica
Published
2026-01-29
DOI
https://doi.org/10.1111/aos.70067
Primary Topic
Corneal surgery and disorders
Type
article
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article

Longitudinal corneal thickness changes and their relation to ocular and systemic cardiovascular risk factors: Results from the Gutenberg Health Study

Joanna Wasielica‐Poslednik, Katharina Geschke, Peter Wolfrum, J. Weinmann‐Menke et al.
Acta Ophthalmologica
Corneal surgery and disorders
article

Longitudinal corneal thickness changes and their relation to ocular and systemic cardiovascular risk factors: Results from the Gutenberg Health Study

Joanna Wasielica‐Poslednik, Katharina Geschke, Peter Wolfrum, J. Weinmann‐Menke, M. E. Beutel, N. Pfeiffer, P. S. Wild, I. Schmidtmann, A. M. Welzel, K. J. Lackner, A. K. Schuster, E. W. Böhm
article en

Abstract

While observing a 5-year decline in CCT, peripheral corneal thickness remained relatively stable. We observed longitudinal associations between CCT changes and HbA1c, lipid profile, mean arterial pressure and smoking, suggesting that corneal thickness changes may be influenced by cardiovascular and metabolic health and thus may be taken into consideration in glaucoma risk stratification.

Acta Ophthalmologica
Johannes Gutenberg University Mainz (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE), German Centre for Cardiovascular Research (DE), Institute of Molecular Biology (DE)
Openalex Percentile: Top 74%
Corneal surgery and disorders
DOISourceOpenAlex
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Longitudinal corneal thickness changes and their relation to ocular and systemic cardiovascular risk factors: Results from the Gutenberg Health Study — Joanna Wasielica‐Poslednik, Katharina Geschke, et al. · Acta Ophthalmologica (2026) | TGRS Research Map | TGRS