Advancing label-free screening technologies to enhance drug discovery efficiency
Label-free assays have rapidly advanced, offering real-time measurements, improved physiological relevance, and expanding throughput for early drug discovery. While these methods reduce artifacts and broaden target compatibility, challenges remain in validating biological relevance and managing complex kinetic data. Recent software innovations, including automated kinetic modeling and high-throughput data pipelines, are accelerating analysis and enhancing scalability.
Authors
- Ronghai Cheng (ORCID: https://orcid.org/0000-0003-4763-8047)
- Chang Liu
Institutions
- Biogen (United States) (US)
Publication Details
- Journal
- Expert Opinion on Drug Discovery
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1080/17460441.2026.2622372
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00