Fuzheng Shengbai decoction enhances antitumor immunity via YTHDC2-dependent stabilization of CLCA2 mRNA in colorectal cancer
FZSB enhances anti-colorectal cancer immune responses and is associated with increased CD8<sup>+</sup> T-cell activation, while concurrently modulating the YTHDC2-CLCA2 axis via m<sup>6</sup>A -mediated mRNA stabilization.
Authors
- Bei Zhang
- Kang Ding
- Juan Chen
- Yu Zhao
- Qin Zheng
- Wenhao Yuan
- Mingzhi Fang
- Min Li
- Yu Wang
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1016/j.jep.2026.121280
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00