Extrapyramidal symptoms and effectiveness of continuous vs bolus intravenous metoclopramide: A systematic review and meta-analysis

In the emergency department, continuous intravenous metoclopramide was associated with a lower risk of EPS without clear differences in symptom control, suggesting that continuous infusion may be a reasonable approach in clinical practice.

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Publication Details

Journal
The American Journal of Emergency Medicine
Published
2026-01-29
DOI
https://doi.org/10.1016/j.ajem.2026.01.051
Primary Topic
Nausea and vomiting management
Type
article
Field-Weighted Citation Impact
0.00
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article

Extrapyramidal symptoms and effectiveness of continuous vs bolus intravenous metoclopramide: A systematic review and meta-analysis

Ryuta Onodera, Yusuke Ogawa, Yoshie Yamada, Takahiro Itaya et al.
The American Journal of Emergency Medicine
Nausea and vomiting management
article

Extrapyramidal symptoms and effectiveness of continuous vs bolus intravenous metoclopramide: A systematic review and meta-analysis

Ryuta Onodera, Yusuke Ogawa, Yoshie Yamada, Takahiro Itaya, Taku Iwami, Yusuke Ito
article en

Abstract

In the emergency department, continuous intravenous metoclopramide was associated with a lower risk of EPS without clear differences in symptom control, suggesting that continuous infusion may be a reasonable approach in clinical practice.

The American Journal of Emergency MedicineVol. 103
Kyoto University (JP)
Openalex Percentile: Top 73%
Nausea and vomiting management
DOIOpen Access PDFOpenAlex
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Extrapyramidal symptoms and effectiveness of continuous vs bolus intravenous metoclopramide: A systematic review and meta-analysis — Ryuta Onodera, Yusuke Ogawa, et al. · The American Journal of Emergency Medicine (2026) | TGRS Research Map | TGRS