Unmasking the impact of cytomegalovirus reactivation in people with advanced HIV disease with <i>Pneumocystis Jirovecii</i> pneumonia: does antiviral therapy change outcomes?

CMV DNA detection in people with HIV hospitalized with PJP was associated with worse outcomes. Anti-CMV therapy was more often used in severe cases and showed an association with in-hospital mortality in unadjusted analyses. The observational design precludes determination of causality.

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Publication Details

Journal
HIV Research & Clinical Practice
Published
2026-01-28
DOI
https://doi.org/10.1080/25787489.2026.2621466
Primary Topic
Pneumocystis jirovecii pneumonia detection and treatment
Type
article
Field-Weighted Citation Impact
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article

Unmasking the impact of cytomegalovirus reactivation in people with advanced HIV disease with Pneumocystis Jirovecii pneumonia: does antiviral therapy change outcomes?

Dita Smíšková, H Rozsypal, D Veselý, Marek Ďuríček et al.
HIV Research & Clinical Practice
Pneumocystis jirovecii pneumonia detection and treatment
article

Unmasking the impact of cytomegalovirus reactivation in people with advanced HIV disease with Pneumocystis Jirovecii pneumonia: does antiviral therapy change outcomes?

Dita Smíšková, H Rozsypal, D Veselý, Marek Ďuríček, Kryštof Šram, David Jilich
article en

Abstract

CMV DNA detection in people with HIV hospitalized with PJP was associated with worse outcomes. Anti-CMV therapy was more often used in severe cases and showed an association with in-hospital mortality in unadjusted analyses. The observational design precludes determination of causality.

HIV Research & Clinical PracticeVol. 27(1)
Charles University (CZ)
Good health and well-being
Openalex Percentile: Top 72%
Pneumocystis jirovecii pneumonia detection and treatment
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