Hypotensive Agents for Controlled Hypotension in Endoscopic Sinus Surgery
In this systematic review and network meta-analysis, controlled hypotension improved surgical field quality in ESS with comparable safety. Diltiazem, esmolol, dexmedetomidine, labetalol, and clonidine were effective; dexmedetomidine was associated with reduced MAP the most, and esmolol favored recovery.
Authors
- Edward D. McCoul (ORCID: https://orcid.org/0000-0003-1812-2105)
- A.I. Saeed (ORCID: https://orcid.org/0000-0001-8660-9578)
- Sara Saleh (ORCID: https://orcid.org/0000-0002-2127-8701)
- Osama Barakat
- Longgang Yu
- M. Elhadi
- Qasi Najah
- Omar Saeed
- Mohamedhen Vall Nounou
- Ahmed Wahhab
Institutions
- University of Aleppo (SY)
- Qingdao University (CN)
- Ochsner Health System (US)
- Hashemite University (JO)
- University of Babylon (IQ)
- Al-Azhar University (EG)
- Korea University (KR)
- Office of Multidisciplinary Activities (US)
- Affiliated Hospital of Qingdao University (CN)
- University Elmergib (LY)
- Korea University (JP)
- Université de Nouakchott (MR)
Publication Details
- Journal
- JAMA Otolaryngology–Head & Neck Surgery
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1001/jamaoto.2025.5222
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00