What to Consider When Developing Multidomain Mobile Health Interventions for Lifestyle Management

Mobile health (mHealth) interventions can transform health care delivery and improve public health. At the same time, the evidence on lifestyle interventions continues to grow. They show promising results in preventing and treating noncommunicable diseases and enhancing health-related quality of life. These factors highlight the potential of multidomain mHealth interventions for lifestyle management. This viewpoint paper focuses on drawing valuable lessons from past experiences and providing guidance to developers of mHealth interventions for lifestyle management. We underscore the critical role of sharing practical insights to advance innovation in the field of mHealth interventions. We used an iterative consensus process to derive lessons learned, identify challenges, and reflect on possible actions. Our insights are based on our experience in developing 2 smartphone-based lifestyle interventions. Challenges and corresponding options in the following areas are presented: target population (preferences, personalization, and delivery), user involvement and testing, human support, and multidomain interventions (interdisciplinarity, flexibility, and core team). The development of multidomain mHealth interventions for lifestyle management requires a participatory and iterative approach involving relevant stakeholders (including end users) so that the right people get the right content at the right time. Additionally, it is crucial to consider established frameworks, guidelines, and regulations; allocate appropriate resources; and form a core team committed to the project's aims and open to working in an interdisciplinary team.