Can Aqueous Proteomics Predict the Recurrence of Rhegmatogenous Retinal Detachment?
The baseline aqueous composition of RD patients that will eventually develop recurrency, differs significantly from those who will not, and already contains molecular signatures that may help identify the risk of recurrency at the time of primary repair. While acknowledging the pilot nature of the study, our findings strongly suggest that Recurrent RD is associated with cell adhesiveness pathways early alterations, offering targets for prognostic assessment and therapy.
Authors
- Guido Ripandelli (ORCID: https://orcid.org/0000-0003-1119-2645)
- TOMMASO ROSSI
- Giuseppe Grasso (ORCID: https://orcid.org/0000-0002-7179-4835)
- Irene Pandino (ORCID: https://orcid.org/0000-0002-1487-9373)
- Diego Sbardella (ORCID: https://orcid.org/0000-0002-9924-7761)
- Luca Placentino
- Gabriele Antonio Zingale (ORCID: https://orcid.org/0000-0003-3059-0534)
- Sara Giammaria
- David H. Steel
- Mario R. Romano
Institutions
- Humanitas University (IT)
- University of Catania (IT)
- Fondazione G.B. Bietti (IT)
- Newcastle University (GB)
Publication Details
- Journal
- Retina
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1097/iae.0000000000004777
- Primary Topic
- Retinal and Macular Surgery
- Type
- article
- Field-Weighted Citation Impact
- 0.00