Case Report: Image-enhanced endoscopic characteristics of gastric amyloidosis with narrow-band imaging comparison

This case highlights the diverse and potentially misleading endoscopic manifestations of GI amyloidosis. NBI may aid in visualizing the distribution pattern and apparent depth of amyloid-related mucosal signals and serve as a supportive diagnostic tool; however, histological confirmation via Congo red staining remains the gold standard. The combination of image-enhanced endoscopy, targeted biopsies, and multidisciplinary evaluation may facilitate earlier recognition and more comprehensive management of patients with atypical gastric erythema.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-29
DOI
https://doi.org/10.3389/fmed.2026.1683757
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
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article

Case Report: Image-enhanced endoscopic characteristics of gastric amyloidosis with narrow-band imaging comparison

Q. Zhang, Bo Lian, Quan Luo, Xintong Jiang et al.
Frontiers in Medicine
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Case Report: Image-enhanced endoscopic characteristics of gastric amyloidosis with narrow-band imaging comparison

Q. Zhang, Bo Lian, Quan Luo, Xintong Jiang, Yan Tang, Tiannu Ding, Jian Dong, Lifeng Hu, Xueman Wang
article en

Abstract

This case highlights the diverse and potentially misleading endoscopic manifestations of GI amyloidosis. NBI may aid in visualizing the distribution pattern and apparent depth of amyloid-related mucosal signals and serve as a supportive diagnostic tool; however, histological confirmation via Congo red staining remains the gold standard. The combination of image-enhanced endoscopy, targeted biopsies, and multidisciplinary evaluation may facilitate earlier recognition and more comprehensive management of patients with atypical gastric erythema.

Frontiers in MedicineVol. 13
Shaoxing University (CN), Shaoxing People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 74%
Amyloidosis: Diagnosis, Treatment, Outcomes
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