Identification of <scp>SDC1</scp> as a Key Regulator and Therapeutic Target in Rheumatoid Arthritis via <scp>JAK2</scp> ‐ <scp>STAT3</scp> Pathway
This study identifies SDC1 as a central hub gene in RA pathogenesis through activation of the JAK2-STAT3 signaling pathway. These findings highlight SDC1 as a potential biomarker for early diagnosis and a promising target for therapeutic intervention, providing new insights into RA management.
Authors
- Gan Cao (ORCID: https://orcid.org/0000-0001-5377-2045)
- Xi Jia
- Yang Sun
- Yatao Du
- Zhihui Wu
- Dongxue Dai
Institutions
- Xi'an Chest Hospital (CN)
- Baoding People's Hospital (CN)
Publication Details
- Journal
- International Journal of Rheumatic Diseases
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1111/1756-185x.70524
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00