Synergistic Antifungal Effects of Honokiol and Fluconazole Against Oral <i>Candida</i> : Implications for Managing Drug‐Resistant Infections

Honokiol demonstrates potent antifungal activity against oral Candida isolates by targeting ergosterol biosynthesis and compromising cell wall integrity. Its synergistic enhancement of Fluconazole's effect suggests clinical potential as an adjunct therapy, potentially reducing resistance and lowering required drug doses in oral and endodontic candidiasis.