Evaluation of shunt valve flow dynamics in series
In all, neither of the two models outperformed the other and both were insufficient to properly characterize the relationship between drainage and opening pressures of valves in series. These results indicate low flowrate variability of isolated valves but high variability of valves placed in series. Without a consistent model from which opening pressure setting of valves in series can be determined, physicians must rely on a trial-and-error method in optimal opening pressure determination which directly impacts patient outcomes. These findings underscore the difficulties faced by physicians in determination of optimal valve settings for shunted patients.
Authors
- Dipankar Biswas (ORCID: https://orcid.org/0000-0002-5594-2236)
- Ryan Lee (ORCID: https://orcid.org/0000-0003-2509-1677)
- Michael Meggyesy
- Kenae Thompson
- Mark Luciano
- Sai C. Reddy
- S. Farzad Maroufi
- Carolyn A. Harris
- Gwendolyn L.M. Williams
Institutions
- Cleveland Clinic (US)
- Johns Hopkins University (US)
- Wayne State University (US)
- Vanderbilt University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1186/s12987-025-00673-6
- Primary Topic
- Cardiovascular and Diving-Related Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00