Evaluation of shunt valve flow dynamics in series

In all, neither of the two models outperformed the other and both were insufficient to properly characterize the relationship between drainage and opening pressures of valves in series. These results indicate low flowrate variability of isolated valves but high variability of valves placed in series. Without a consistent model from which opening pressure setting of valves in series can be determined, physicians must rely on a trial-and-error method in optimal opening pressure determination which directly impacts patient outcomes. These findings underscore the difficulties faced by physicians in determination of optimal valve settings for shunted patients.

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Publication Details

Journal
Fluids and Barriers of the CNS
Published
2026-01-29
DOI
https://doi.org/10.1186/s12987-025-00673-6
Primary Topic
Cardiovascular and Diving-Related Complications
Type
article
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article

Evaluation of shunt valve flow dynamics in series

Dipankar Biswas, Ryan Lee, Michael Meggyesy, Kenae Thompson et al.
Fluids and Barriers of the CNS
Cardiovascular and Diving-Related Complications
article

Evaluation of shunt valve flow dynamics in series

Dipankar Biswas, Ryan Lee, Michael Meggyesy, Kenae Thompson, Mark Luciano, Sai C. Reddy, S. Farzad Maroufi, Carolyn A. Harris, Gwendolyn L.M. Williams
article en

Abstract

In all, neither of the two models outperformed the other and both were insufficient to properly characterize the relationship between drainage and opening pressures of valves in series. These results indicate low flowrate variability of isolated valves but high variability of valves placed in series. Without a consistent model from which opening pressure setting of valves in series can be determined, physicians must rely on a trial-and-error method in optimal opening pressure determination which directly impacts patient outcomes. These findings underscore the difficulties faced by physicians in determination of optimal valve settings for shunted patients.

Fluids and Barriers of the CNSVol. 23(1)
Cleveland Clinic (US), Johns Hopkins University (US), Wayne State University (US), Vanderbilt University (US), Johns Hopkins Medicine (US)
Openalex Percentile: Top 74%
Cardiovascular and Diving-Related Complications
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Evaluation of shunt valve flow dynamics in series — Dipankar Biswas, Ryan Lee, et al. · Fluids and Barriers of the CNS (2026) | TGRS Research Map | TGRS