Prothrombinase again, but different this time

signaling, both leading to phosphorylation of eukaryotic initiation factor-2 and culminating in a reduction of protein synthesis and increased apoptosis.These downstream markers could eventually serve as pharmacodynamic biomarkers or predictors of response. 5

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Publication Details

Journal
Blood
Published
2026-01-29
DOI
https://doi.org/10.1182/blood.2025032020
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Prothrombinase again, but different this time

Shekhar Kumar
Blood
Blood Coagulation and Thrombosis Mechanisms
article

Prothrombinase again, but different this time

Shekhar Kumar
article en

Abstract

signaling, both leading to phosphorylation of eukaryotic initiation factor-2 and culminating in a reduction of protein synthesis and increased apoptosis.These downstream markers could eventually serve as pharmacodynamic biomarkers or predictors of response. 5

BloodVol. 147(5)
California University of Pennsylvania (US)
Zero hunger
Openalex Percentile: Top 76%
Blood Coagulation and Thrombosis Mechanisms
DOIOpen Access PDFOpenAlex
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Prothrombinase again, but different this time — Shekhar Kumar · Blood (2026) | TGRS Research Map | TGRS