Oncogenic Signaling Activation and Potential Biomarkers in Congestive Hepatopathy Revealed by Proteomic Analysis
PCL upregulated oncogenic proteins and activated oncogenic signaling pathways. DEPs detectable in the liver and serum indicate potential FALD biomarkers. These findings offer insights into the pathophysiology of FALD and hepatocarcinogenesis and support the development of novel diagnostic and therapeutic strategies.
Authors
- Yoshie Fukasawa
- Naoki Ohashi (ORCID: https://orcid.org/0000-0002-4011-0031)
- Yoshihito Morimoto (ORCID: https://orcid.org/0000-0002-7696-3159)
- Hidenori Yamamoto (ORCID: https://orcid.org/0000-0001-7950-6482)
- Kiyotaka Go (ORCID: https://orcid.org/0000-0001-9206-4033)
- Taichi Kato (ORCID: https://orcid.org/0000-0001-7084-4565)
- Kentaro Suzuki
- Yoshiyuki Takahashi
Institutions
- Fukuoka Children's Hospital and Medical Center for Infectious Diseases (JP)
- National Cerebral and Cardiovascular Center (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1111/hepr.70133
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00