Development and validation of a nomogram for predicting positive [99mTc]Tc-HYNIC-PSMA SPECT/CT in patients with biochemically recurrent prostate cancer after radical prostatectomy

This study introduces a novel nomogram predicting the likelihood of [99mTc]Tc-HYNIC-PSMA SPECT/CT imaging positivity in PCa patients with BCR post-radical prostatectomy. The nomogram enhances patient stratification and may optimize the selection of candidates for PSMA SPECT/CT imaging, thereby improving clinical decision-making and patient outcomes.

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Publication Details

Journal
Nuclear Medicine Communications
Published
2026-01-29
DOI
https://doi.org/10.1097/mnm.0000000000002118
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Development and validation of a nomogram for predicting positive [99mTc]Tc-HYNIC-PSMA SPECT/CT in patients with biochemically recurrent prostate cancer after radical prostatectomy

Xinyu Wu, Xintao Ding, Y. Yu, Yuan Gao et al.
Nuclear Medicine Communications
Prostate Cancer Treatment and Research
article

Development and validation of a nomogram for predicting positive [99mTc]Tc-HYNIC-PSMA SPECT/CT in patients with biochemically recurrent prostate cancer after radical prostatectomy

Xinyu Wu, Xintao Ding, Y. Yu, Yuan Gao, Yuqing Du, Feifei He, Guang Yang, Wenliang Li, Bo Li
article en

Abstract

This study introduces a novel nomogram predicting the likelihood of [99mTc]Tc-HYNIC-PSMA SPECT/CT imaging positivity in PCa patients with BCR post-radical prostatectomy. The nomogram enhances patient stratification and may optimize the selection of candidates for PSMA SPECT/CT imaging, thereby improving clinical decision-making and patient outcomes.

Nuclear Medicine Communications
Henan Provincial People's Hospital (CN), Henan Cancer Hospital (CN), Columbia University (US)
Reduced inequalities
Openalex Percentile: Top 74%
Prostate Cancer Treatment and Research
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Development and validation of a nomogram for predicting positive [99mTc]Tc-HYNIC-PSMA SPECT/CT in patients with biochemically recurrent prostate cancer after radical prostatectomy — Xinyu Wu, Xintao Ding, et al. · Nuclear Medicine Communications (2026) | TGRS Research Map | TGRS