Association of severe depression with bone mineral content: a mediation analysis in PERSIAN cohort study
Severe depression level demonstrates both direct and indirect associations with BMC, along with interactions with smoking and the falling asleep duration as mediators. All the mediators exhibit a pure direct association with BMC. Nevertheless, it appears that our confounding variables exert a strong influence on these relationships, as most of the associations were not significant after adjustment.
Authors
- Fateme Nikbakht (ORCID: https://orcid.org/0000-0003-1761-0887)
- Ali Moradi (ORCID: https://orcid.org/0000-0003-1966-3819)
- Samaneh Eslami
- Ali Taghipour (ORCID: https://orcid.org/0000-0002-6876-5902)
- Mahdieh Sahebi (ORCID: https://orcid.org/0000-0003-1053-7760)
- Mahla. Daliri
- Masoumeh Sadeghi
- Mohammad H. Ebrahimzadeh
Institutions
- Mashhad University of Medical Sciences (IR)
- Torbat Heydarieh University of Medical Sciences (IR)
- University of Torbat Heydarieh (IR)
- Ghaem Hospital (IR)
Publication Details
- Journal
- BMC Public Health
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1186/s12889-026-26261-3
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00