Reproductive and obstetric outcomes following frozen embryo transfer: letrozole combined with human menopausal gonadotropin versus hormone replacement cycle

Adjusted analysis revealed comparable LBR between the OI and HRT protocols. The OI protocol was associated with a lower risk of cesarean section and GDM in the overall population, with exploratory subgroup analyses suggesting potential differential effects in specific patient groups. These findings warrant prospective validation.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-29
DOI
https://doi.org/10.3389/fendo.2026.1698208
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Reproductive and obstetric outcomes following frozen embryo transfer: letrozole combined with human menopausal gonadotropin versus hormone replacement cycle

Jia Song, Huijuan Guan, Hui Li, Jiahui Zhao et al.
Frontiers in Endocrinology
Ovarian function and disorders
article

Reproductive and obstetric outcomes following frozen embryo transfer: letrozole combined with human menopausal gonadotropin versus hormone replacement cycle

Jia Song, Huijuan Guan, Hui Li, Jiahui Zhao, Yan-Lan Hao, Huai-Yun Tang, Li-Sha Tang
article en

Abstract

Adjusted analysis revealed comparable LBR between the OI and HRT protocols. The OI protocol was associated with a lower risk of cesarean section and GDM in the overall population, with exploratory subgroup analyses suggesting potential differential effects in specific patient groups. These findings warrant prospective validation.

Frontiers in EndocrinologyVol. 17
Lianyungang Maternal and Children’s Hospital (CN)
Good health and well-being
Openalex Percentile: Top 75%
Ovarian function and disorders
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Reproductive and obstetric outcomes following frozen embryo transfer: letrozole combined with human menopausal gonadotropin versus hormone replacement cycle — Jia Song, Huijuan Guan, et al. · Frontiers in Endocrinology (2026) | TGRS Research Map | TGRS