Supplementation With <i>Lactococcus lactis</i> LMG 27352: Lack of Beneficial Effects on Cardiometabolic Risk in Obese Patients Without Concomitant Dietary Intervention—A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial
The findings of this study suggest limited clinical efficacy of <i>L lactis</i> LMG 27352 supplementation in metabolic disorders related to obesity under the conditions investigated. These results underscore the critical influence of dietary patterns, particularly sodium and carbohydrate intake, which may have modulated or counteracted any potential benefits of the probiotic strain.
Authors
- Andrezza Fernanda Santiago
- Bianca Aparecida de Sousa (ORCID: https://orcid.org/0000-0003-3743-0541)
- Camila Maria de Melo
- Melissa Aparecida Morais
- Lívia Borges Rodrigues Silva
- Luíz Gustavo dos Santos
- Maria Luiza Dutra Souza
- Leandra Passarelli Castro e Souza
- Isabela Coelho de Castro
- João Paulo Lima de Oiveira
- Yasmin Maria Borges Barolli Reis
Institutions
- Universidade Federal de Lavras (BR)
Publication Details
- Journal
- Journal of the American Nutrition Association
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1080/27697061.2025.2610805
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00